产品货号:
Z23978
中文名称:
PD-1/CD279/PDCD1抗体
英文名称:
Anti-PD-1/CD279/PDCD1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PD-1/CD279/PDCD1 Antibody |
指标别名 | CD279;hPD 1;hPD l;PD 1;PD1;PD-1;PD-1/CD279;PDCD1;programmed cell death 1;Protein PD 1;SLEB2 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB |
基因名称 | PDCD1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human PD1 recombinant protein (Position:P101-L288).Human PD1 shares 59% amino acid (aa) sequence identity with mouse PD1. |
实际分子量 | 65KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | PDCD1(Programmed cell death 1),also called PD1,encodes a cell surface receptor that is a member of the B7 superfamily involved in immunomodulation.This gene is mapped to 2q37.3.PDCD1 acts as an inhibitory molecule on T cells after interacting with its ligands PDL1 and PDL2.The PDCD1 gene contains 5 exons.This protein is expressed in pro-B-cells and is thought to play a role in their differentiation.Using flow cytometric analysis,It has been found that expression of PDCD1 was upregulated on CD16-positive and CD16-negative monocytes,but not on dendritic cells,in viremic HIV-positive patients,but not in highly active antiretroviral therapy (HAART)-treated HIV-positive patients.PDCD1 upregulation in monocytes was induced by microbial Toll-like receptor ligands and inflammatory cytokines. |
Uniprot ID | Q15116 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | programmed cell death 1 |
蛋白名全称 | Programmed cell death protein 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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